five

High-throughput sequencing of zebrafish wild-type and duox mutant larvae

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP246913
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资源简介:
To determine the molecular basis for the dual oxidase in circulation in duox mutant zebrafish, we performed high-throughput sequencing at 4 dpf. Results revealed 375 up-regulated genes and 360 down-regulated genes in the duox mutant zebrafish compared with wild-type zebrafish. We found that some mitochondrial genes are down-regulated in duox mutant zebrafish, which was reconfirmed with qRT-PCR. Overall design: mRNA profiles of 4 dpf wild-type and duox mutant zebrafish were generated by deep seqeuncing.
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2020-12-13
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