X-ray crystal structure of CYP142 from Mycobacterium tuberculosis in complex with a fragment bound in two poses

X-ray crystal structure of CYP142 from Mycobacterium tuberculosis in complex with a fragment bound in two poses Descriptor: 4-benzylpyridine, PROTOPORPHYRIN IX CONTAINING FE, Steroid C26-monooxygenase Authors: Snee, M, Kavanagh, M, Levy, C, Leys, D. Deposit date: 2024-02-22 Release date: 2025-01-29 Last modified: 2025-08-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Fragment-Based Development of Small Molecule Inhibitors Targeting Mycobacterium tuberculosis Cholesterol Metabolism. J.Med.Chem., 68, 2025