Small ruminant isolates, attack rates, and survival times in tg338 mice.#

#abbreviations: Obx, obex; cbl, cerebellum; Cbr, cerebrum; n.a. not available; Ni, number of mice inoculated; Nd, number of mice diseased¶as reported in our previous study [17]; -, structure missing; 1, mild; 2, moderate; 3, severe.*for S4/RS fourteen out of sixteen inoculated mice died within two days post inoculation, most probably due to a high bacterial contamination of the sample.§polymorphisms of the PRNP alleles are shown for position 136, 141,154 and 171 for the atypical scrapie isolates and for positions 136, 154 and 171 for the classical scrapie control. Alleles associated with relative susceptibility with atypical scrapie are indicated in bold.