CD8+ T cell responses specific for ts-derived peptides with high representation in the T. cruzi genome in HLA-A2.1+ patients with chronic Chagas disease, measured by IFN-�� ELISPOT.
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(A)All the peptides assayed were recognized by spleen cells from T. cruzi-infected A2 transgenic mice (25).(B)Number of annotated T. cruzi genes containing indicated epitopes (13).(C)Number of proteins containing indicated epitopes identified in T. cruzi proteome (59).(D)Number of alleles of the HLA-A2 supertype bound.(E)Mean values was obtained from responders subjects. (*) P = 0.04 vs. G2/G3 (Fisher's exact test).
创建时间：
2015-12-02
