Structure of full-length amyloidogenic immunoglobulin light chain H9 in complex with 6-methyl-2-(2-((1E,2E)-3-(2-nitrophenyl)allylidene)hydrazineyl)pyrimidin-4-ol

Structure of full-length amyloidogenic immunoglobulin light chain H9 in complex with 6-methyl-2-(2-((1E,2E)-3-(2-nitrophenyl)allylidene)hydrazineyl)pyrimidin-4-ol Descriptor: 6-methyl-2-{2-[(1E)-3-(2-nitrophenyl)prop-1-en-1-yl]hydrazin-1-yl}pyrimidin-4(5H)-one, H9 immunoglobulin light chain, PHOSPHATE ION Authors: Yan, N.L, Wilson, I.A, Kelly, J.W. Deposit date: 2022-12-29 Release date: 2023-05-24 Last modified: 2026-04-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structures of Diaryl Hydrazone and Sulfone Stabilizers in Complex with an Amyloidogenic Light Chain Reveal an Alternate Ligand-Binding Cavity Isr.J.Chem., 2023