Table_1_Acceptance and commitment therapy reduces psychological distress in patients with cancer: a systematic review and meta-analysis of randomized controlled trials.DOCX

ObjectiveThis study aimed to systematically review and meta-analyze the clinical efficacy of acceptance and commitment therapy (ACT) in patients with cancer and psychological distress.MethodsRandomized controlled trials (RCTs) from seven English electronic databases were systematically investigated from inception to 3 October 2023. A total of 16 RCTs from 6 countries with 711 participants were included in this study. Estimated pooled effect sizes (ESs) were calculated via inverse-variance random-effects or fixed-effects (I2 ≤ 50%) model and presented by standardized mean difference (SMD). Subgroup analyses were performed to reduce confounding factors and heterogeneity, and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system was used to evaluate the quality of the pooled ESs.ResultsThe pooled ESs revealed that statistically significant improvements in anxiety [postintervention SMD = −0.41 (95% confidence interval (CI), −0.71, −0.11); p = 0.008; I2 = 65%; follow-up SMD = −0.37 (95% CI, −0.66, −0.08); p = 0.01; I2 = 29%], depression [postintervention SMD = −0.45 (95% CI, −0.63, −0.27); p

本研究旨在系统性地回顾和元分析癌症患者伴心理痛苦状态下接受与承诺疗法（ACT）的临床疗效。方法上，对截至2023年10月3日从七个英语电子数据库中检索的随机对照试验（RCTs）进行了系统调查。本研究共纳入来自6个国家的16项RCTs，参与人数共计711人。通过逆方差随机效应或固定效应（I2≤50%）模型计算了估计的汇总效应量（ESs），并以标准化平均差异（SMD）的形式呈现。为了降低混杂因素和异质性，进行了亚组分析，并采用建议、评估、发展和评价分级系统（GRADE）对汇总ESs的质量进行了评估。结果显示，汇总ESs表明在焦虑[干预后SMD=−0.41（95%置信区间（CI），−0.71，−0.11）；p=0.008；I2=65%；随访SMD=−0.37（95% CI，−0.66，−0.08）；p=0.01；I2=29%]，抑郁[干预后SMD=−0.45（95% CI，−0.63，−0.27）；p