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Evolutionary adaptations of Pseudomonas aeruginosa biofilms to combined treatment of ciprofloxacin and an antioxidant in synthetic sputum media
This study examined how antioxidants influence the evolution of ciprofloxacin resistance in Pseudomonas aeruginosa PAO1 biofilms grown in synthetic cystic fibrosis sputum medium (SCFM2). Experimental
NIAID Data Ecosystem40
Supplementary Table S4 from Combinatorial Screening of Pancreatic Adenocarcinoma Reveals Sensitivity to Drug Combinations Including Bromodomain Inhibitor Plus Neddylation Inhibitor
Contribution of agents to filtered combinations
NIAID Data Ecosystem10
Mesenchymal-like tumor cells and myofibroblastic cancer-associated fibroblasts are associated with progression and immunotherapy response of clear-cell renal cell carcinoma [scRNA-seq]. Mesenchymal-like tumor cells and myofibroblastic cancer-associated fibroblasts are associated with progression and immunotherapy response of clear-cell renal cell carcinoma [scRNA-seq]
Immune checkpoint inhibitors (ICI) represent the cornerstone for treatment of patients with metastatic clear-cell renal cell carcinoma (ccRCC). Despite a favorable response for a subset of patients, o
NIAID Data Ecosystem10
Investigating Immune and Non-Immune Cell Interactions in Head and Neck Tumors by Single-Cell RNA Sequencing
Head and neck squamous cell carcinoma (HNSCC) is characterized by complex relations between stromal, epithelial, and immune cells within the tumor microenvironment (TME). To enable the development of
NIAID Data Ecosystem30
Table1_The Chemokines Initiating and Maintaining Immune Hot Phenotype Are Prognostic in ICB of HNSCC.xlsx
Background: The immune checkpoint blockade (ICB) with anti-programmed cell death protein 1(PD-1) on HNSCC is not as effective as on other tumors. In this study, we try to find out the key factors in t
NIAID Data Ecosystem10
