Cochlear tuning in early aging estimated with three methods

Age-related hearing loss (ARHL) currently affects over 20 million adults in the U.S., and its prevalence is expected to increase as the population ages. However, little is known about the earliest manifestations of ARHL, including its influence on auditory function beyond the threshold of sensation. This work explores the effects of early aging on frequency selectivity (i.e., ‘tuning’), a critical feature of normal hearing function. Tuning is estimated using both behavioral and physiological measures – fast psychophysical tuning curves (fPTC), distortion product otoacoustic emission level ratio functions (DPOAE LRFs), and stimulus-frequency OAE (SFOAE) phase gradient delay. All three measures were selected because they have high potential for clinical translation but have not been compared directly in the same sample of ears. Results indicate that there may be subtle changes in tuning during early aging, even in ears with clinically normal audiometric thresholds. Additionally, there are..., These data were collected as part of CCG's dissertation experiments at Northwestern University. They have subsequently been used to prepare a manuscript for publication. Associated code for plotting/data analysis for this manuscript can be found on GitHub: https://github.com/cobycoburn/Cochlear-Tuning-in-Early-Aging-Estimated-with-Three-Methods, , # Data from: Cochlear tuning in early aging estimated with three methods

[https://doi.org/10.5061/dryad.7m0cfxq5d](https://doi.org/10.5061/dryad.7m0cfxq5d)

## Description of the data and file structure

Files include:

1\) allData25-Jun-2024.csv: fPTC data for each participant, including derived Qerb estimates

2\) audioData_2024-05-13.csv: Audiometric thresholds from participants

3\) indvLRFQ2024-06-28.csv: DPOAE LRF data for each participant, including derived Qerb estimates

4\) participantTestEar.csv: Test ear of each participant

5\) sfPhase.csv: SFOAE phase data from each participant, including derived Qerb estimates. Note that Qerb*_*S is the column used for data analysis in this manuscript

6\) Cochlear-Tuning-in-Early-Aging-Estimated-with-Three-Methods-main.zip: R Code used to analyze data and plot manuscript figures. This code is also available in a GitHub Repo (Public Archive). 

Note that some of the.csv files contain data from participants who were not included in the fi...,