Effect of Sulfopin and Abemaciclib treatment on gene expression in mouse TNBC

To investigate the role of combined PIN1 and CDK4 inhibition in the regulation of immune response, we performed RNA sequencing of TNBC tumors after treatment with Sulfopin, Abemaciclib or their combination We then performedgene set enrichment analyses using data obtained from RNA-seq of different treatments. Comparative analysis of immune response signatures in single-drug treatment and combination treatment using RNA-sequencing data.