Chitosan Schiff base Ruthenium(III) complexes

Chitosan can be modified chemically by condensation reaction of deacetylated chitosan with aldehydein homogeneous phase. This condensation is carried by primary amine ( NH2) with aldehyde ( CHO)to form corresponding schiff base. The chitosan biopolymer schiff base derivatives are synthesized withsubstituted aldehydes namely 4-hydroxy-3-methoxy benzaldehyde, 2-hydroxy benzaldehyde, and 2-hydroxy-3-methoxy benzaldehyde, becomes a complexing agent or ligand. The Ruthenium(III) complexeswere obtained by complexation of Ruthenium with schiff base ligands and this product exhibits as anexcellent solubility and more biocompatibility. The novel series of schiff base Ruthenium(III) complexesare characterized by Elemental analysis, FT-IR spectroscopy, and Thermo-gravimetric analysis (TGA). Thesynthesized complexes have been subjected to antibacterial study. The antibacterial results indicated thatthe antibacterial activity of the complexes were more effective against Gram positive and Gram negativepathogenic bacteria. These findings are giving suitable support for developing new antibacterial agentand expand our scope for applications.