Gut microbiota of obese children relates to intestinal inflammation and metabolic phenotype worsening.. Gut microbiota assessment in children with obesity and insulin resistance

Through massive sequencing of 16S rRNA gene amplicons (V4-V5) and data analysis using a novel permutation approach, we have detected decreased incidence of Blautia species, especially B. luti and B. wexlerae, in the gut microbiota of obese children, which was even more pronounced in cases with both obesity and insulin resistance.