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DA-DRD5 signaling controls colitis by regulating M1M2 colonic macrophage polarization

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NIAID Data Ecosystem2026-03-12 收录
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Previous studies have suggested that the dynamic shifts in gut microbiota play a significant role during the development of colitis. To evaluate whether the increased severity in colitis observed in DRD5-/- mice is also driven by colitogenic microbiota, we cohoused littermate WT mice [WT (DRD5-/-)] and DRD5-/- mice [DRD5-/- (WT)] for six weeks to equalize bacterial community before the administration of DSS

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2020-09-18
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