Genome wide analysis of binding of Polyhomeotic and polymerization defective Polyhomeotic in Drosophila S2 cells. Drosophila melanogaster

To understand the role of the conserved Sterile Alpha Motif of the Polycomb Group protein Polyhomeotic, the genome wide distribution of wild type and polymerization defective Polyhomeotic containing mutations in the SAM domain was determined by ChIP-SEQ. Overall design: ChIP-seq Identification of polyhomeotic wild type (PH-WT) and mutant (PH-ML) binding sites.