Crystal structure of Dot1L in complex with inhibitor CPD11 [N4-methyl-N2-(2-methyl-1-(2-phenoxyphenyl)-1H-indol-6-yl)pyrimidine-2,4-diamine]
收藏Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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Crystal structure of Dot1L in complex with inhibitor CPD11 [N4-methyl-N2-(2-methyl-1-(2-phenoxyphenyl)-1H-indol-6-yl)pyrimidine-2,4-diamine] Descriptor: Histone-lysine N-methyltransferase, H3 lysine-79 specific, N~4~-methyl-N~2~-[2-methyl-1-(2-phenoxyphenyl)-1H-indol-6-yl]pyrimidine-2,4-diamine, ... Authors: Scheufler, C, Gaul, C, Be, C, Moebitz, H. Deposit date: 2015-09-17 Release date: 2016-06-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach. Acs Med.Chem.Lett., 7, 2016
创建时间：
2015-09-17
