Dissecting the specific role of Oct4 during the early stage of reprogramming

ChEBI2014-05-13 更新2026-07-21 收录

干细胞重编程

转录因子功能分析

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-47061 数据链接链接失效反馈

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Dissecting the specific role of Oct4 during the early stage of reprogramming

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2014-05-13

Proteomic Analysis of Intracellular Proteins in Aeromonas hydrophila Reveals the Role of the AraC-Type Transcription Factor ORF02889 in Virulence Regulation

毒力机制

转录因子功能分析

Proteomic Analysis of Intracellular Proteins in Aeromonas hydrophila Reveals the Role of the AraC-Type Transcription Factor ORF02889 in Virulence Regulation

integrated proteome resources50

Transcription factor NKX3-1 is required for reprogramming to pluripotency and can replace OCT4 in mouse and human iPSC induction [ATAC-seq]. Homo sapiens

干细胞重编程

转录因子功能

Resolution of early molecular events preceding endogenous OCT4 activation is critical to understanding the mechanism of reprogramming somatic cells to induced pluripotent stem cells (iPSCs), yet captu

NIAID Data Ecosystem40

α-Ketoglutarate inhibits the pluripotent-to-totipotent state transition

干细胞重编程

代谢调控机制

In early mouse embryogenesis, the distinct enrichment of α-ketoglutarate (αKG) in blastocysts and L-2-hydroxyglutarate (L-2HG) in 2-cell (2C) embryos serves as a key metabolic signature. While elevate

NIAID Data Ecosystem30

Processed data for Figure 2 and 3

合成基因电路调控

转录因子功能分析

90 E.coli TFs encompassing regulation of several key cellular functions were profiled on synthetic circuits to isolate the fundamental response function. Each regulator was assayed at 3 binding

Figshare2025-01-15 更新40

Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency [RNA-seq]. Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency [RNA-seq]

干细胞重编程

染色质可及性调控

Chemical induction of pluripotency (CIP) is an ideal way to reprogram cell fate, but remains poorly understood. Here we report the development of an efficient CIP protocol and the chromatin accessibil

NIAID Data Ecosystem40

Dissecting the specific role of Oct4 during the early stage of reprogramming

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