Pelvic floor muscle response after simulated birth injury and mechanisms of a skeletal muscle-derived ECM hydrogel (SKM). Pelvic floor muscle response after simulated birth injury and mechanisms of a skeletal muscle-derived ECM hydrogel (SKM)

Time course of pelvic floor muscles response was investigated, together with the efficacy of an ECM hydrogel therapy. Overall design: A custom codeset panel to investigate pathways known to regulate appendicular muscles’ response to injury: immune response, myogenesis, muscle anabolism and catabolism, ECM remodeling, neovascularization, and neuromuscular junction development and maturation