Significantly deregulated genetic networks as identified by the Ingenuity Pathways Analysis (IPA).

The table displays the seven functional networks identified by the IPA as significantly (score>3) associated with the geneset defined by the two critera (1) deregulated between patients and controls according to LAP or (2) t-test<0.05 and Fold Change>1.5. The table displays the genes associated with the functional networks (genes which are present in the uploaded gene set are in bold). The arrows behind a gene indicate the direction of change (arrow pointing upwards: increased expression in patients, arrow pointing downwards: decreased expression in patients).The column ‘score’ gives the significance score for the network. The column ‘# of genes’ gives the number of genes in the network. Each network consists –by definition of the IPA- of 35 genes. The last column shows the functions in which each network is predominantly involved.