Structure of PAK1 in complex with compound 16
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Structure of PAK1 in complex with compound 16 Descriptor: N~2~-{[(1R,3R,4S)-4-amino-3-(3-chlorophenyl)cyclohexyl]methyl}-N~4~-(5-cyclopropyl-1,3-thiazol-2-yl)pyrimidine-2,4-diamine, Serine/threonine-protein kinase PAK 1 Authors: Dementiev, A, Suto, R.K, Olland, A.M. Deposit date: 2024-08-13 Release date: 2025-04-02 Last modified: 2025-07-16 Method: X-RAY DIFFRACTION (1.847 Å) Cite: Identification of a p21-activated kinase 1 (PAK1) inhibitor with 10-fold selectivity against PAK2. Bioorg.Med.Chem.Lett., 127, 2025
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2024-08-13
