Copper-Catalyzed Synthesis of Quinoxalines with o-Phenylenediamine and Terminal Alkyne in the Presence of Bases

A novel way of synthesizing quinoxalines efficiently through cyclization of o-phenylenediamine and terminal alkyne by Cu(II) and bases is developed. This reaction proceeds smoothly to give the products in moderate to good yields.

本研究成功开发了一种高效合成喹唑啉的新方法，通过Cu(II)和碱性物质对对苯二胺及端炔烃的环化反应实现。该反应过程流畅，产品收率适中至良好。