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Reaction of Dimethoxycarbene−DMAD Zwitterion with 1,2-Diones and Anhydrides: A Novel Synthesis of Highly Substituted Dihydrofurans and Spirodihydrofurans

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Reaction_of_Dimethoxycarbene_DMAD_Zwitterion_with_1_2_Diones_and_Anhydrides_A_Novel_Synthesis_of_Highly_Substituted_Dihydrofurans_and_Spirodihydrofurans/3232588
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The zwitterion formed by the reaction of dimethoxycarbene and DMAD adds efficiently to one of the carbonyl groups of 1,2-dicarbonyl compounds and anhydrides to generate dihydrofurans and spirodihydrofurans in good yields. In many cases, the carbene inserts into the C−C bond of the dione to yield masked vicinal tricarbonyl systems.
创建时间:
2006-03-17
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