liverTox_ALT_target

The data come from a liver toxicity study in which 64 male rats were exposed to non-toxic (50 or 150 mg/kg),moderately toxic (1500 mg/kg) or severely toxic (2000 mg/kg) doses of acetaminophen (paracetamol) (Bushel, Wolfinger, and Gibson 2007).Necropsy was performed at 6, 18, 24 and 48 hours after exposure and the mRNA was extracted from the liver.Ten clinical measurements of markers for liver injury are available for each subject.The microarray data contain expression levels of 3,116 genes. The data were normalised and preprocessed by Bushel, Wolfinger, and Gibson (2007).