Quantitative proteomic analysis of iron oxide nanoparticles toxicity in rats
收藏国家人口健康科学数据中心2026-06-01 收录
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https://www.ncmi.cn/phda/dataDetails.do?id=CSTR:17970.11.A001G.202308.1931.V1.0
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资源简介：
Iron oxide nanoparticles (IONPs) are the first generation of nanomaterials approved by the Food and Drug Administration for use as imaging agents and for the treatment of iron deficiency in chronic kidney disease. However, several IONPs-based imaging agents have been withdrawn because of toxic effects and the poor understanding of the underlying mechanisms. This study aimed to evaluate IONPs toxicity via proteomics and to elucidate the underlying mechanism after intravenous administration in rats.
提供机构：
北京蛋白质组研究中心创建时间：
2022-08-11
