Lactate-driven lactylation of histone H3K18 and AIF orchestrates parthanatos in pulmonary microvascular endothelial cells in sepsis-induced acute lung injury

We are pleased to submit the original data for our manuscript entitled “Lactate-driven lactylation of histone H3K18 and AIF orchestrates parthanatos in pulmonary microvascular endothelial cells in sepsis-induced acute lung injury” to Mendeley Data. This dataset contains all CUT&Tag, ATAC-seq, single-cell sequencing, and proteomics sequencing data generated in this study. To request access to the dataset, interested researchers should submit a formal application to the corresponding author, Prof. Mengmeng Xu ([e-mail]), clearly stating the intended academic and non-commercial research purpose. Access will be granted only after review and approval by the institutional data access committee.