Crystal Structure of BACE-1 in complex with AHM178
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Crystal Structure of BACE-1 in complex with AHM178 Descriptor: Beta-secretase 1, N-acetyl-L-leucyl-N-[(4S,5S,7R)-8-(butylamino)-5-hydroxy-2,7-dimethyl-8-oxooctan-4-yl]-L-methioninamide Authors: Rondeau, J.-M. Deposit date: 2009-10-07 Release date: 2010-05-05 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure-based design and synthesis of novel P2/P3 modified, non-peptidic beta-secretase (BACE-1) inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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2009-10-07
