THE BURDEN OF SYSTEMIC INFLAMMATION AND MULTIORGAN INVOLVEMENT IN ANKYLOSING SPONDYLITIS: CLINICAL PATTERNS AND THERAPEUTIC PERSPECTIVES
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Ankylosing spondylitis (AS) is a prototypical form of axial spondyloarthritis characterized by chronic inflammation of the sacroiliac joints and spine, progressive structural damage, and functional impairment. Historically regarded as a disease confined to the axial skeleton, AS is now understood as a systemic inflammatory disorder with diverse clinical expressions.
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2026-03-13



