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Poly-alanine model for HL-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (open conformation)

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Protein Data Bank Japan2025-08-06 更新2026-05-23 收录
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Poly-alanine model for HL-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (open conformation) Descriptor: Epidermal growth factor receptor, HL-type bispecific diabody Ex3, T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 epsilon chain Authors: Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y. Deposit date: 2024-07-10 Release date: 2025-05-28 Last modified: 2025-08-06 Method: ELECTRON MICROSCOPY (3.85 Å) Cite: Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement. Cell Rep, 44, 2025

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2024-07-10
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