Raw data of gender differences and risk factors for AKI

The research data for this study was sourced from the electronic medical record database of the First Affiliated Hospital of Wenzhou Medical University. The statistics and perioperative data analyzed in this study include: age, gender, height, weight, preoperative echocardiography and laboratory examination, previous medical histories such as myocardial infarction, CPB time, arterial blood gas examination during cardiopulmonary bypass, and postoperative laboratory examination.The diagnosis of AKI was made using the improved global prognostic criteria (KDIGO) by comparing the postoperative serum creatinine level with the preoperative serum creatinine level. Patients were classified into stages 1-3 of AKI. Stage 1 was defined as an increase in serum creatinine by more than 26.5 μmol/L within 2 days after cardiac surgery, or an increase in serum creatinine to more than 1.5 times the preoperative level within 7 days after the procedure. Stage 2 was defined as an increase in serum creatinine to 2.0-2.9 times the baseline level. Stage 3 was defined as an increase in serum creatinine to 3 times baseline or ≥4.0 mg/dl (≥353.6 μmol/l) increase, or initiation of RRT. The KDIGO urine volume standard for AKI was not utilized in this study.Between January 1, 2020, and December 31, 2021, a total of 1040 adult patients underwent cardiac surgery with cardiopulmonary bypass (CPB) at the First Affiliated Hospital of Wenzhou Medical University. Among these patients, 781 were included in the study (see appendix) and had a mean age of 57.92 ± 12.99 years, with a range of 18 to 85 years. Of these patients, 402 (51.47%) were male. Among the 781 patients, 236 were diagnosed with acute kidney injury (AKI), resulting in an incidence of 30.22% after surgery. The incidence of AKI was higher in the older group, with 40.7% (161/396) of patients over the age of 60 developing AKI, compared to 19.5% (75/385) of patients in the younger group.