The chromatin remodeller ATRX interacts with the histone chaperone DAXX, to deposit the histone variant H3.3 at sites of nucleosome turnover. ATRX is known to bind repetitive, heterochromatic regions
We applied CRISPR gene-editing to induce t(4;11) chromosomal translocations in primary human umbilical cord blood (UCB) hematopoietic stem and progenitor cells (HSPCs) to faithfully model leukemias wi
ATAC-seq in NrESC_1, NrESC_16, ESC, EPSC Embryonic stem cells upon extrinsic induction could self-assemble into blastocyst-like structures. However, the intrinsic regulation of such blastoid forming p
