Antibodies targeting the neuraminidase active site inhibit influenza H3N2 viruses
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Contemporary influenza A H3N2 viruses circulating since 2016 have acquired a glycosylation site in the neuraminidase in close proximity to the enzymatic active site. Here, we investigate if this S245N glycosylation site, as a result of antigenic evolution, can impact binding and function of human monoclonal antibodies that target the conserved active site.
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ImmPort创建时间:
2024-09-20



