Risk factors for hospital mortality (global analysis).

APACHE–Acute Physiological and Chronic Health Evaluation, SOFA–Sequential Organ Failure Assessment, ICU–intensive care unit, CVP–central venous pressure, ScvO–central venous oxygen saturation, OR–odds ratio, CI–confidence interval, NS–non-significant, NA–not applicable, significant variable in the univariate analysis but not included in the multivariate analysis due to missing data. The results are expressed as a number (%) or median (25%–75%). *Total number of patient variables according to the bundle evaluated [(fluid resuscitation (n = 243), vasopressors (n = 198), CVP and Scv0? (n = 197)]. ** only those not in previous antibiotics use or in whom the previous antibiotics was changed. (public: n = 115, public: n = 187).*** Approximately currency: 1R = 1.8 US. Chi-squared and Mann Whitney tests (univariate). Multivariate analysis with stepwise forward regression, reference: non-survivors. Hosmer-Lemeshow test p = 0.19.