Nanopores with an Engineered Selective Entropic Gate DetectProteins at Nanomolar Concentration in Complex Biological Sample

This dataset belongs to the article: "Nanopores with an Engineered Selective Entropic Gate DetectProteins at Nanomolar Concentration in Complex Biological Sample" published in JACS (DOI: 10.1021/jacs.4c17147) and contains the raw electrophysiology data of protein capture by engineered YaxAB, analysis MATLAB scripts and analysis Excel files. For YaxAB_JACS_2025.zip: - Each electrophysiology file contains measurement info as follows:[Date of measurement]_[Buffer conditions]_[Pore type]_[added analyte(s)]_[operator initials] - Each electrophys trace is accompanied by Excel file with Clampfit analysis in Sheet1 (named [voltage], with the columns corresponding to: Trace; Search; Level; State; Event Start Time (ms); Event End Time (ms); Amplitude (pA); Amp S.D. (pA); Dwell Time (ms); Inst. Freq. (Hz); Interevent Interval (ms); [empy]; open pore current (pA) - This Excel sheet was analyzed with inhouse MATLAB script; and event data (Iex, dwell time, Amp S.D.) is placed in second sheet of Excel file. - A summary of all the event data (mean +/- S.D.) for all replicates is in a separate Excel file in the corresponding folder. This dataset contains one replicate per experiment. Raw data for all replicates can be shared upon reasonable request.