Crystal structure of the L428V mutant of pregnane X receptor ligand binding domain in complex with SJPYT-331
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Crystal structure of the L428V mutant of pregnane X receptor ligand binding domain in complex with SJPYT-331 Descriptor: DIMETHYL SULFOXIDE, Nuclear receptor subfamily 1 group I member 2, Nuclear receptor coactivator 1 fusion protein,Nuclear receptor coactivator 1, ... Authors: Garcia-Maldonado, E, Huber, A.D, Nithianantham, S, Miller, D.J, Chen, T. Deposit date: 2023-05-17 Release date: 2024-05-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR. Nat Commun, 15, 2024
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2023-05-17
