PTIR1 acts as a suppressor of immunoproteasome and promotes cancer immune resistance
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE168862
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资源简介：
Cancer cells evade host immune surveillance by virtue of poor immunogenicity. We identify a novel oncogene that acts as a promotor of tumor immune resistance, designated as PTIR1. Tumor-intrinsic PTIR1 is induced by RNA splicing and highly correlated with poor outcome of patients with cancer. Study of tumor infiltration lymphocytes in Mock or PTIR1 expressing CT26 tumors using 10x scRNA-seq technologies.
创建时间：
2024-02-19
