The Discovery of 2-Substituted Phenol Quinazolines as Potent and Selective RET Kinase Inhibitors
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The Discovery of 2-Substituted Phenol Quinazolines as Potent and Selective RET Kinase Inhibitors Descriptor: 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET Authors: Newton, R, Bowler, K, Burns, E.M, Chapman, P, Fairweather, E, Fritzl, S, Goldberg, K, Hamilton, N.M, Holt, S.V, Hopkins, G.V, Jones, S.D, Jordan, A.M, Lyons, A, McDonald, N.Q, Maguire, L.A, Mould, D.P, Purkiss, A.G, Small, H.F, Stowell, A, Thomson, G.J, Waddell, I.D, Waszkowycz, B, Watson, A.J, Ogilvie, D.J. Deposit date: 2015-03-11 Release date: 2016-02-17 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.57 Å) Cite: The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity. Eur J Med Chem, 112, 2016
创建时间：
2015-03-11
