High-throughput screening (Alphascreen<sup>®</sup>) system for inhibitors that block the interaction between the PLZF and HB-EGF- or AR-CTF.
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Compounds: 9,000 → 12, Z’-factor: 0.73±0.091, S/B: 20.6, *not calculated. Twelve candidate and four angiotensin II type 1 receptor blocker (ARB) based on efficacy for blocking binding of HB-EGF-CTF or AR-CTF to Zn5-8 of PLZF with Alphascreen system. Z’-factor showed to be 0.73 (0.5
创建时间：
2013-02-22
