HUMAN PRMT5:MEP50 Crystal Structure With MTA and Fragment Bound
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HUMAN PRMT5:MEP50 Crystal Structure With MTA and Fragment Bound Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, CHLORIDE ION, GLYCEROL, ... Authors: Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J. Deposit date: 2022-05-16 Release date: 2022-10-19 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Rsc Med Chem, 13, 2022
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2022-05-16
