Synthesis of Pyrido-Fused Quinazolinone Derivatives via Copper-Catalyzed Domino Reaction
收藏Figshare2016-02-12 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Synthesis_of_Pyrido_Fused_Quinazolinone_Derivatives_via_Copper_Catalyzed_Domino_Reaction/2074771
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资源简介：
A simple and efficient synthesis of 11H-pyrido[2,1-b]quinazolin-11-ones by Cu(OAc)2·H2O-catalyzed reaction of easily available substituted isatins and 2-bromopyridine derivatives has been developed. The reaction involves C–N/C–C bond cleavage and two C–N bond formations in a one-pot operation. This methodology is complementary to previously reported synthetic procedures, and two plausible reaction mechanisms are discussed.
创建时间：
2016-02-12
