Cathepsin K covalently bound to a cyano-pyrimidine inhibitor with improved selectivity over hERG
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Cathepsin K covalently bound to a cyano-pyrimidine inhibitor with improved selectivity over hERG Descriptor: 3-{2-[(E)-iminomethyl]-6-propylpyrimidin-4-yl}-N,N-dimethyl-5-(trifluoromethyl)benzamide, Cathepsin K Authors: Fradera, X, van Zeeland, M, Uitdehaag, J.C.M. Deposit date: 2010-07-20 Release date: 2011-03-30 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: improving selectivity over hERG. Bioorg.Med.Chem.Lett., 20, 2010
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2010-07-20
