Autoantibody associations passing a genome-wide association significance threshold in the GWA scan (MHC excluded).

Non-MHC SNPs passing a genome-wide significance threshold p<5×10−8 when scanning the genome for association with IA-2A, GADA, PCA, and TPOA. p-values and odds ratios (OR, estimated for the minor allele and 95% confidence intervals (CI)) were obtained using logistic regression (1 df trend test). We controlled for significant covariates (sex, time since diagnosis and age at bleed). The sample size N indicates the number of autoantibody negative/positive individuals. Antibody status was coded as a binary variable (Methods). Note that we listed the nearest gene, which does not imply that this gene is causal.