Asymmetric Chlorocyclization of Indole-3-yl-benzamides for the Construction of Fused Indolines
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(DHQD)2PHAL catalyzed enantioselective chlorocyclization of indole-3-yl-benzamides was realized. Fused indolines containing a continuous quaternary carbon center and tertiary carbon center were obtained in good yields with excellent enantioselectivity (up to 98% yield and >99% ee).
创建时间：
2016-02-17
