Human TLR8 bound to the potent agonist, GS-9688 (Selgantolimod)
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Human TLR8 bound to the potent agonist, GS-9688 (Selgantolimod) Descriptor: (2R)-2-[(2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-yl)amino]-2-methylhexan-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 8, ... Authors: Appleby, T.C, Perry, J.K, Mish, M, Villasenor, A.G, Mackman, R.L. Deposit date: 2020-04-21 Release date: 2021-02-03 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Discovery of GS-9688 (Selgantolimod) as a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B. J.Med.Chem., 63, 2020
创建时间：
2020-04-21
