Crystal structure of thiol peroxidase mutant (C94A) in complex with Metro-P3* (H. pylori)

Crystal structure of thiol peroxidase mutant (C94A) in complex with Metro-P3* (H. pylori) Descriptor: 3-methyl-2-(prop-2-ynoxymethyl)imidazol-4-amine, Thiol peroxidase Authors: Fiedler, M.K, Gong, R, Fuchs, S, Rox, K, Friedrich, V, Pfeiffer, D, Reinhardt, T, Mibus, C, Huber, M, Hess, C, Mejias-Luque, R, Gerhard, M, Groll, M, Sieber, S.A. Deposit date: 2024-04-30 Release date: 2025-05-14 Last modified: 2026-04-22 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Metronidazole and ether derivatives target Helicobacter pylori via simultaneous stress induction and inhibition. Nat Microbiol, 11, 2026