Distribution of non-synonymous variations between non-malignant samples and CaCx cases across the coding regions of the HPV16 intact isolates.

The percentage of non synonymous variations was estimated on the basis of total number of non synonymous variations out of total number of nucleotides (normalized with the size of the ORFs) in cases or non-malignant samples within the respective ORFs; e.g. For E4: % within cases = [100/(287×70)]×100 and % within non-malignant samples = [27/(287×25)]×100.
Bold emphasis indicates statistically significant p-values.