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Canonical Nlrp3 inflammasome activation links systemic age-related inflammation with functional decline

ChEBI2013-09-05 更新2026-07-21 收录

炎症小体机制

衰老免疫学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-43034 数据链接链接失效反馈

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资源简介：

Canonical Nlrp3 inflammasome activation links systemic age-related inflammation with functional decline

应用场景：

创建时间：

2013-09-05

神经损伤修复

衰老免疫学

Pro-regenerative macrophages are well known for their role in promoting tissue repair, however in aging macrophage numbers are reduced acutely and repair following nerve injury deminished. Macrophage-

NIAID Data Ecosystem90

Gene expression of unperturbed young and aged mouse bladders. Gene expression of unperturbed young and aged mouse bladders

衰老免疫学

膀胱组织转录组

Aging has multifaceted effects on the immune system, but how aging affects tissue-specific immunity is not well-defined. Bladder diseases characterized by chronic inflammation are highly prevalent in

NIAID Data Ecosystem50

Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging II. Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging II

衰老免疫学

单细胞转录组学

To gain insight into the mechanisms by which exercise affects circulating immune cells, we subjected young and old mice to aerobic exercise and performed single cell transcriptome analysis of circulat

NIAID Data Ecosystem40

Inflammasome activation drives inflammation in hidradenitis suppurativa skin. Inflammasome activation drives inflammation in hidradenitis suppurativa skin

化脓性汗腺炎免疫学

炎症小体机制

Treatment for the debilitating, chronic skin disease hidradenitis suppurativa (HS) is grossly inadequate. A better understanding of its pathogenesis is required to design new therapeutic strategies. D

NIAID Data Ecosystem50

Additional file 11 of Age-associated changes in the circulating human antibody repertoire are upregulated in autoimmunity

衰老免疫学

自身免疫抗体库

Additional file 11: Table S3. Same as Table S1, but for Verification Cohort (Experiment 1116).

NIAID Data Ecosystem40