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Pkd1 and Pkd2 mRNA cis-inhibition drives polycystic kidney disease progression

NIAID Data Ecosystem2026-03-13 收录

多囊肾病机制

基因表达调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE196237 数据链接链接失效反馈

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资源简介：

We report the findings of deletion of the miR17 binding motif from Pkd1 mRNA examination of RNA from whole kidney lysates from control and cystic

应用场景：

创建时间：

2022-08-26

基因表达调控

内质网应激

Transcriptome was used to analyze the over-expression of NAC091D(removing the transmembrane domain) and to study the transcriptional changes of related genes under ER stress

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Table3_A Core Response to the CDX2 Homeoprotein During Development and in Pathologies.XLSX

基因表达调控

癌症分子机制

Whether a gene involved in distinct tissue or cell functions exerts a core of common molecular activities is a relevant topic in evolutionary, developmental, and pathological perspectives. Here, we ad

NIAID Data Ecosystem20

Chromatin loop dynamics during cellular differentiation are associated with changes to both anchor and internal regulatory features [dataset 4]

染色质三维结构动态

基因表达调控

3D chromatin structure is thought to play a critical role in regulating gene transcription during cellular transitions. While our understanding of loop formation and maintenance is rapidly improving,

NIAID Data Ecosystem20

CD4 T cell transcriptome and RARα. CD4 T cell transcriptome and RARα

免疫细胞转录组学

基因表达调控

Transcriptome assessment by RNAseq was performed on 24h-activated naïve CD4+ T cells with variables of RARα expression and RA concentration. Overall design: Naïve CD4 T cells isolated from WT, RARα KO

NIAID Data Ecosystem30

Differentially expressed transcriptomes of NADases mutant in Arabidopsis

基因表达调控

昼夜节律转录组

The purpose of this experiment is to find differentially expressed genes in Arabidopsis NADases mutant in daytime and night time. This result indicated that PARPs regulate the expression of only a few

NIAID Data Ecosystem20

Pkd1 and Pkd2 mRNA cis-inhibition drives polycystic kidney disease progression

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