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SCOPE system-based peptide screening against EphA2 by phage display

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NIAID Data Ecosystem2026-03-14 收录
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Molecular selection for affinity ligand generation is the key cornerstone of biology, medicine, and pharmacology research, as well as clinical applications. However, generating high-affinity ligands has still proven challenging and time-consuming for most methods. Herein, we present a microfluidic platform (named SCOPE) to realize highly-efficient affinity-discriminated molecular selection, highlighting in synergy of both force and concentration effects into molecular equilibrium shifting.

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2022-09-23
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