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Fragmentomics of urinary cell-free DNA in nuclease knockout mouse models

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NIAID Data Ecosystem2026-03-13 收录
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Urinary cell-free DNA (ucfDNA) is a potential biomarker for bladder cancer detection. However, the biological characteristics of ucfDNA are not well understood. We explored the roles of deoxyribonuclease 1 (DNASE1) and deoxyribonuclease 1-like 3 (DNASE1L3) in the fragmentation of ucfDNA using mouse models.

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2022-05-28
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