Bulk-RNA Sequencing of Rhesus Macaque Trophoblast Organoids

While primate placentas exhibit many shared morphological features, species-specific differences in gene expression remain largely unexplored, primarily due to the lack of suitable in vitro models. To address this gap, we developed organoids from rhesus macaque placentas, including trophoblast and maternal-derived decidua types. We performed bulk-RNA sequencing to define the transcriptional signatures of the rhesus macaque placenta.