Crystal Structure of Human MMP-13 complexed with a (pyridin-4-yl)-2H-tetrazole compound
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Crystal Structure of Human MMP-13 complexed with a (pyridin-4-yl)-2H-tetrazole compound Descriptor: 4-[(5-{2-[(3-fluorobenzyl)carbamoyl]pyridin-4-yl}-2H-tetrazol-2-yl)methyl]benzoic acid, CALCIUM ION, Collagenase 3, ... Authors: Shieh, H.-S, Collins, B, Schnute, M.E. Deposit date: 2009-10-26 Release date: 2010-11-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis. Bioorg.Med.Chem.Lett., 20, 2010
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2009-10-26
