Targeting IDH1 as a pro-senescent therapy in high-grade serous ovarian cancer. Targeting IDH1 as a pro-senescent therapy in high-grade serous ovarian cancer
收藏NIAID Data Ecosystem2026-03-11 收录
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We found that targeting IDH1 in HGSC induces senescence by altering the repressive histone landscape of E2F target genes Overall design: Ovcar3 cells were infected with control or shIDH1. Cells were selected in 3ug/mL puromycin for 7 days. RNA was isolated and RNA-seq was performed comparing control and knockdown RNA.
创建时间：
2019-03-21
